Risk and Impulsive Behaviour, Depression Among Adolescentsthrough the Prism of Neuroimaging Studies of Brain Development

  • Lence Miloseva
  • Vladimir Milosev

Abstract

Adolescence is a specific developmental period in which there are social and cognitive developmental prerequisites for the emergence of vulnerability to risky and impulsive behaviors, and affective occurrence of disorders, such as depression. Review of literature and reference researchshows that traditional neurobiological and cognitive explanations for adolescent behavior have failed to explainnonlinear behavioral changes observed in adolescence, associated with childhood and adult life. We made a review of referenced research imaging studies with magnetic resonance imaging (MRI), diffusion tensor imaging (DTI) studies, functional magnetic resonance imaging (fMRI) studies of development of the human brain and behavior, neuroimaging studies and depression in adolescence, in order to provide explaination of:nonlinear changes behavior observed in adolescence and neural mechanisms responsible for these changes; individual differences in optimal decision-making and behavior during adolescence. The findings of these studies suggest that during adolescence, unlike childhood and adulthood, there is a differential development of bottom-up limbic system, implicated in motivational and emotional processes, to topdown control system. These developmental patterns can be intensify in adolescents who are more prone to emotional responsiveness, increasing the probability of the occurrence of risky and impulsive outcomes. We emphasized the need for new longitudinal neuroimaging studies, which include the dimension of development.

Downloads

Download data is not yet available.

References

Alloy, L. B., Abramson, L.Y., Walshaw, P.D., Keyser, J., & Gerstein, R. K. (2006). A cognitive vulnerability–stress perspective on bipolar spectrum disorders in a normative adolescent brain, cognitive, and emotional development context. Development and Psychopathology ,18, 1055–1103.

Blumberg, H.P., Kaufman, J., Martin, A., Whiteman, R., Zhang, J.H., Gore, J.C., Charney, D.S., Krystal, J.H., Peterson,B.S. (2003a). Amygdale and hippocampal volumes in adolescents and adults with bipolar disorder. Archivesof General Psychiatry. 60,1201–1208.

Bjork, J. M., Knutson, B., Fong, G. W., Caggiano, D. M., Bennett, S. M., & Hommer, D. W. (2004). Incentiveelicited brain activation in adolescents: Similarities and differences from young adults. Journal of Neuroscience, 24, 1793–1802.

Bourgeois, J. P., Goldman-Rakic, P. S., & Rakic, P. (1994). Synaptogenesis in the prefrontal cortex of rhesus monkeys. Cerebral Cortex, 4, 78–96.

Botteron, K.N., Raichle, M.E., Drevets, W.C., Heath, A.C., Todd, R.D.(2002). Volumetric еduction in left subgenualprefrontal cortex in early onset depression. Biological Psychiatry,15,342–344.

Benthin, A., Slovic, P., & Severson, H. (1993). A psychometric study of adolescent risk perception. Journal of Adolescence, 16, 153–168.

Bjork, J. M., Knutson, B., Fong, G. W., Caggiano, D. M., Bennett, S. M., & Hommer, D. W. (2004). Incentiveelicited brain activation in adolescents: Similarities and differences from young adults. Journal of Neuroscience, 24, 1793–1802.

Bourgeois, J. P., Goldman-Rakic, P. S., & Rakic, P. (1994). Synaptogenesis in the prefrontal cortex of rhesus monkeys. Cerebral Cortex, 4, 78–96.

Brainerd, C. J., & Reyna, V. F. (1993). Memory independence and memory interference in cognitive development. Psychological Review, 100, 42–67.

Brown, T. T., Lugar, H. M., Coalson, R. S., Miezin, F. M., Petersen, S. E., & Schlaggar, B. L. (2005). Developmental changes in human cerebral functional organization for word generation. Cerebral Cortex, 15,275–290.

Bunge, S. A., Dudukovic, N. M., Thomason, M. E., Vaidya, C. J., & Gabrieli, J. D.

(2002). Immature frontal lobe contributions to cognitive control in children:

Evidence from fMRI. Neuron, 33, 301–311.

....................

Published
2013-05-28